Cyclodextrins G. K. E Scriba, M.-L. Konjaria, S. Krait, in Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, Q. B Cass, M. L. Tiritan, J.C. Barreiro, M. Batista Junior (editors), John Wiley & Sons, Hoboken, 2023, 273-323.
Quality by design-guided development of a capillary electrophoresis method for the chiral purity determination of silodosin A. Modroiu, S. Krait, G. Hancu, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2023, 222, 115117.
Cyclodextrins as Chiral Selectors in Capillary Electrophoresis: Recent Trends in Mechanistic Studies B. Chankvetadze, G. K. E. Scriba, Trends Anal. Chem. 2023, 160, 116987.
Isothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by g-cyclodextrin and trimethyl-β-cyclodextrin P. Peluso, D. Landy, L. Nklhle, Dallocchio, A. Dessì, S. Krait, A. Salgado, B. Chankvetadze, G. K. E. Scriba, Carbohydr. Polym. 2023, 313, 120870.
2022
Structural characterization of methyl-β-cyclodextrins by high-performance liquid chromatography and nuclear magnetic resonance spectroscopy and effect of their isomeric composition on the capillary electrophoresis enantioseparation of daclatasvir S. Krait, A. Salgado, M. Malanga, T. Sohajda, G. Benkovics, P. S. Szakály, B. Chankvetadze, G. K. E. Scriba, J. Chromatogr. A 2022, 1661, 462675.
Enantioseparation of chiral (benzylsulfinyl)benzamide sulfoxides by capillary electrophoresis using cyclodextrins as chiral selectors. M.-L. Konjaria, R. Kakava, A. Volonterio, B. Chankvetadze, G. K. E. Scriba, J. Chromatogr. A 2022, 1672, 463027.
Quality by design-assisted development of a capillary electrophoresis method for the enantiomeric purity determination of tenofovir. S. Krait, F. R. Schneidmadel, G. K. E. Scriba, Electrophoresis 2022, 43, 964-969.
Kapillarelektrophorese (in German) P. Schmitt-Kopplin, G. K. E. Scriba, in Bioanalytik, J. Kurreck, J. W. Engels, F. Lottspeich (editors), 4th edition, Springer Spektrum, Heidelberg, 2022, 299-325.
2021
12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets S. Liening, J. Fischer, H. Jagusch, G. Pohnert, O. Höcker, C. Neusüß, O. Werz, G. K. E. Scriba, U. Garscha, Prostaglandins Other Lipid Mediat. 2021, 152, 1006480.
Global Testing of a Consensus Solubility Assessment to Enhance Robustness of the WHO Biopharmaceutical Classification System V. Gigante, G. M. Pauletti, S. Kopp, M. Xu, I. Gonzalez-Alvarez, V. Merino, Mi. McIntosh, A. Wessel, B. J. Lee, K. Rocha Rezende, G. K. E. Scriba, G. P. Singh, M. Bermejo, ADMET & DMPK 2021, 9, 23-39.
Combined cardioprotective and adipocyte browning effects promoted by the eutomer of dual sEH/PPARγ modulator M. Hartmann, I.-S. Bibli, D. Tews, X. Ni, T. Kirchner, J. S. Kramer, W. Kilu, J. Heering, V. Hernandez-Olmos, L. Weizel, G. K. E. Scriba, S. Krait, S. Knapp, A. Chaikuad, D. l Merk, I. Fleming, P. Fischer-Posovszky, E. Proschak, J. Med. Chem. 2021, 64, 2815-2828.
HPLC-MS Identification of Acid Degradation Products of Dolutegravir S. Krait, D. K. Wissenbach, F. T. Peters, G. K. E Scriba, J. Pharm. Biomed. Anal. 2021, 197, 113954.
Effects of amino acid-derived chiral ionic liquids on cyclodextrin-mediated enantioseparations of dipeptides M. L. Konjaria, G. K. E. Scriba, J. Chromatogr. A 2021, 1652, 4662342.
Complexation of daclatasvir by methylated cyclodextrins studied by capillary electrophoresis and nuclear magnetic resonance spectroscopy S. Krait, A. Salgado, P. Peluso, M. Malanga, T, Sohajda, G, Benkovics, L. Naumann, C. Neusüß, B. Chankvetadze, G. K. E Scriba, Carbohydr. Polym. 2021, 273, 118486.
Advances of Capillary Electrophoresis Enantioseparations in Pharmaceutical Analysis (2017 - 2020) S. Krait, M.-L. Konjaria, G. K. E. Scriba, Electrophoresis 2021, 42, 1709-1725
2020
Quality by design-based development of a chiral capillary electrophoresis method for the determination of dextrodropropizine and 1-phenylpiperazine as impurities in levodropropizine. S. Niedermeier, G. K. E. Scriba, Chromatographia 2020, 83, 123-129.
Enantioseparation of analogs of the dipeptide alanyl-phenylalanine by capillary electrophoresis using neutral cyclodextrins as chiral selectors M. L. Konjaria, G. K. E. Scriba, J. Chromatogr. A 2020, 1623, 461158
Chiral separation of four phenothiazines by nonaqueous capillary electrophoresis and quality by design-based method development for quantification of dextromepromazine as chiral impurity of levomepromazine S. Niedermeier, G. K. E. Scriba, J. Chromatogr. A 2020, 1624, 461232.
Liquid chromatographic method for the simultaneous determination of achiral and chiral impurities of dapoxetine in approved and counterfeit products G. Tóth, E. Fogarasi, A. Bartalis-Fábián, M. Foroughbakhshfasaei, I. Boldizsár, A, Darcsi, S. Lohner, G. K. E. Scriba, Z. I. Szabó, J. Chromatogr. A 2020, 1626, 461388.
Unusual Complexation Behavior between Daclatasvir and g-Cyclodextrin. A Multiplatform Study S. Krait, A. Salgado, C. Villani, L. Naumann, C. Neusüß, B. Chankvetadze, G. K. E Scriba, J. Chromatogr. A 2020, 1628, 461448.
Enantioseparation of analogs of the dipeptide alanyl-phenylalanine by capillary electrophoresis using negatively charged cyclodextrins as chiral selectors M. L. Konjaria, G. K. E. Scriba, J. Chromatogr. A 2020, 1632, 461585.
2019
Capillary Electrophoresis Method for the Determination of (R)-Dapoxetine, (3S)-3-(Dimethylamino)-3-phenyl-1-propanol, (S)-3-Amino-3-phenyl-1-propanol and 1-Naphthol as Impurities of Dapoxetine Hydrochloride H. Harnisch, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2019, 162, 257-263.
Differential Pulse Polarographic Investigation of Micafungin and Anidulafungin Using a Dropping Mercury Electrode H. Knoth, G- K. E. Scriba, S. Langnäse, B. Büttner, Pharmazie 2019, 74, 18-22.
Cyclodextrin-Mediated Capillary Electrophoresis Enantioseparation of Dansylated β-Amino Acids with Bicyclo[2.2.2]octane, Bicyclo[3.1.1]heptane and Cyclopenta[d][1,2]oxazole core Structures H. Harnisch, I. Ilisz, F. Fülöp, Z. Szakonyi, L. Kiss, A. Péter, G. K. E. Scriba, Electrophoresis 2019, 40, 1931-1940.
Capillary Electrophoresis, Pharmaceutical Applications G. K. E. Scriba, in Encyclopedia of Analytical Science, 3rd edition, vol. 2, Elsevier, Amsterdam 2019, 387-399; doi.org/10.1016/B978-0-12-409547-2.14236-2.
Chiral Recognition in Separation Science – An Overview G. K. E. Scriba, in Chiral Separations, Methods and Protocols, 3rd edition, Methods in Molecular Biology Vol. 1985, G. K. E. Scriba (editor), Humana Press, 2019, 1-33.
Cyclodextrins as Chiral Selectors in Capillary Electrophoresis Enantioseparations G. K. E. Scriba, P. Jac, in Chiral Separations, Methods and Protocols, 3rd edition, Methods in Molecular Biology Vol. 1985, G. K. E. Scriba (editor), Humana Press, 2019, 339-356.
Capillary Electrophoresis-Based Enzyme Assays for β-Lactamase EnzymesC. Chen, J. S. Kramer, S. Brunst, E. Proschak, G. K.E. Scriba, Electrophoresis 2019, 40, 2375-2381.
Chiral Recognition in Separation Sciences. Part I: Polysaccharide and Cyclodextrin SelectorsG. K. E. Scriba, Trends Anal. Chem. 2019, 120, 115639.
Chiral Recognition in Separation Sciences. Part II: Macrocyclic Glycopeptide, Donor-Acceptor, IonExchange, Ligand-Exchange and Micellar SelectorsG. K. E. Scriba, Trends Anal. Chem. 2019, 119, 115628.
Enantioselective resolution of biologically active dipeptide analogs by high-performance liquid chromatography applying Cinchona alkaloid-based ion-exchanger chiral stationary phasesA. Bajtai, I. Ilisz, D. H. O. Howan, G. K. Tóth, G. K. E. Scriba, W. Lindner, A. Péter, J. Chromatogr. A 2019, 1611, 460574
2018
Analysis of Small Molecule Drugs, Excipients and Counter Ions in Pharmaceuticals by Capillary Electromigration Methods – Recent Developments. Q. Zhu, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2018, 147, 425-438.
Development of a Capillary Electrophoresis Method for the Determination of the Chiral Purity of Dextromethorphan by a Dual Selector System using Quality by Design Methodology. S. Krait, M. Heuermann, G. K. E. Scriba, J. Sep. Sci. 2018, 41, 1405-1413.
Capillary Electrophoresis Method for the Chiral Purity Determination of Pregabalin Derivatized with Dansyl Chloride. H. Harnisch. Y. Chien, G. K. E. Scriba, Chromatographia 2018, 81, 719-725.
Simultaneous Determination of Related Substances and Dextromepromazine in Levomepromazine on a Cellulose tris(4-Methylbenzoate) Chiral Column. S. Niedermeier, I. Matarashvili, B. Chankvetadze, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2018, 158, 294-299.
Investigation of the Complexation between Cyclodextrins and Medetomidine Enantiomers by Capillary Electrophoresis, NMR Spectroscopy and Molecular Modeling. S. Krait, A. Salgado, B. Chankvetadze, F. Gago, G. K. E Scriba, J. Chromatogr. A 2018, 1567, 198-210.
Capillary Electrophoresis-Based Enzyme Assay for Nicotinamide N-Methyltransferase. C. Chen, D. Bönisch, R. Penzis, T. Winckler, G. K. E. Scriba, Chromatographia 2018, 81, 1439-1444.
Quality by Design-Assisted Development of a Capillary Electrophoresis Method for the Chiral Purity Determination of Dexmedetomidine. S. Krait, G. K. E. Scriba, Electrophoresis 2018, 39, 2575-2580.
2017
Raman spectroscopy and capillary zone electrophoresis for the analysis of degradation processes in commercial effervescent tablets containing acetylsalicylic acid and ascorbic acid. S. Neuberger, K. Jooß, D. Flottmann, G. K. E. Scriba, C. Neusüß, J. Pharm. Biomed. Anal. 2017, 134, 122-129.
Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase. U. Garscha, E. Romp, S. Pace, A. Rossi, V. Temml, D. Schuster, S. König, J. Gerstmeier, S. Liening, H. Atze, S. Wittmann, C.Weinigel, S. Rummler, G. K. E. Scriba, L. Sautebin, O. Werz, Sci. Rep. 2017, 7(1), 9398.
A Quality by Design-Based Approach to a Capillary Electrokinetic Assay for the Determination of Dextromepromazine and Levomepromazine Sulfoxide as Impurities of Levomepromazine. S. Niedermeier, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2017, 146, 402-409.
2016
Structural and Chiroptical Analysis of Naturally Occurring (-)-Strychnine. F. Reinscheid, M. Schmidt, H. Abromeit, S. Liening, G. K. E. Scriba, U. M. Reinscheid, J. Mol. Struct. 2016, 1106, 200-209.
Recent Advances in Capillary Electrophoretic Migration Techniques for Pharmaceutical Analysis (2013-2015). S. El Deeb, H. Wätzig, D. A. El-Hady, C. Sänger-van de Griend, G. K. E. Scriba, Electrophoresis 2016, 37, 1591-1608.
Stereospecific capillary electrophoresis assays using pentapeptide substrates for the study of Aspergillus nidulans methionine sulfoxide reductase A and mutant enzymes. Q. Zhu, R. G. El-Mergawy, Y. Zhou, C. Chen, S. H. Heinemann, R. Schönherr, D. Robaa, W. Sippl, G. K. E. Scriba, Electrophoresis 2016, 37, 2083-2090.
Chiral Recognition in Separation Science – An Update. G. K. E. Scriba, J. Chromatogr. A 2016, 1467, 56-78.
Quality by Design-Guided Development of a Capillary Electrophoresis Method for the Chiral Purity Determination of Ambrisentan. S. Krait, M. Douša, G. K.E. Scriba, Chromatographia 2016, 79, 1343-1350.
Development of a cell-free and cell-based assay system to elucidate novel leukotriene C4-synthase inhibitors. S. Liening, S. Rummler, C. Weinigel, T. K. Kleinschmidt, J. Haeggström, G. K. E. Scriba, Oliver Werz, U. Garscha, Biochim.Biophys. Acta 2016, 1861, 1605-1613.
BRP-187: a potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase / 5-lipoxygenase activating protein (FLAP) complex assembly . S. Voelker, U. Garscha, S. Pace, J. Gerstmeier, B. Emini, S. Liening, C. Weinigel, S. Rummler, U. S. Schubert, G. K. E. Scriba, E.Çelikoğlu, E. Banoglu, L. Sautebin, O. Werz, Biochem. Pharmacol., 2016, 119, 17-26.
Advances in the Use of Cyclodextrins as Chiral Selectors in Capillary Electromigration Techniques – Fundamentals and Applications. Q. Zhu, G. K. E. Scriba, Chromatographia 2016, 79, 1403-1435.
Development and validation of a CZE method for the characterization of sulfoethyl cellulose. H. Harnisch, J. Hühner, C. Neusüß, A. Koschella, T. Heinze, G. K. E. Scriba, J. Sep. Sci. 2016, 39, 4645-4652.
2015
Electrochemical Behaviour of the Antifungal Agents Itraconazole, Posaconazole and Ketoconazole at a Glassy Carbon Electrode. H. Knoth, G. K. E. Scriba, B. Büttner, Pharmazie 2015, 70, 374-378.
Advances in Capillary Electrophoresis-Based Enzyme Assays. G. K. E. Scriba, F. Belal, Chromatographia 2015, 78, 947-970.
2014
Recent Advances in Capillary Electrophoretic Migration Techniques for Pharmaceutical Analysis. S. El Deeb, H. Wätzig, D. El Hady, H. Al Bishri, C. Sänger-van de Griend, G. K. E. Scriba, Electrophoresis 2014, 35, 170-189.
Hidden Flexibility of Strychnine. M. Schmidt, F. Reinscheid, H. Sun, H. Abromeit, G. K. E. Scriba, F. D. Sönnichsen, M. John, U. M. Reinscheid, Eur. J. Org.Chem. 2014, 1147-1150.
Stereospecific electrophoretically mediated microanalysis assay for methionine sulfoxide reductase enzymes. Q. Zhu, R. G. El-Mergawy, S. H. Heinemann, R. Schönherr, P. Jáč, G. K. E. Scriba, Anal. Bioanal. Chem. 2014, 406, 1723-1729.
Effect of Caffeine-Containing Beverages on Physicochemical and Release Properties of Halofantrine. C. P. Babalola, Y. T. Kolade, M. A. Adeyemo, O. A. Kotila, S. J. Ameh, T. A. Adelakun, S. G. N. K. Adewuyi, G. K. E. Scriba, Glob.J. Med. Res. B 2014, 14,
Experimental design-guided development of a stereospecific capillary electrophoresis assay for methionine sulfoxide reductase enzymes using a diastereomeric pentapeptide substrate. Q. Zhu, X. Huo, S. H. Heinemann, R. Schönherr, R. El-Mergawy, G. K. E. Scriba, J. Chromatogr. A 2014, 1359, 224-229.
Cyclodextrin-mediated enantioseparation of phenylalanine amide derivatives and amino alcohols by capillary electrophoresis – role of complexation constants and complex mobilities. A. Aranyi, A. Péter, I. Ilisz, F. Fülöp, G. K. E. Scriba, Electrophoresis 2014, 35, 2848-2854.
Capillary electrophoresis separation of methionine sulfoxide containing peptide diastereomers by dual cyclodextrin-crown ether systems. Q. Zhu, S. H. Heinemann, R. Schönherr, G. K. E. Scriba, J. Sep. Sci. 2014, 37, 3458-3354.
Characterization of Hydrothermally Treated Beech Wood Xylan by Capillary Electrophoresis with Laser-Induced Fluorescence and Mass Spectrometry Detection. P. Jáč, T. Elschner, C. Reiter, S.-C. Bunz, H.-M. Vorbrodt, A. Pfeifer, C. Neusüß, T. Heinze, G. K. E. Scriba, Cellulose, 2014, 21, 3993-4007.
2013
Comparative Enantioseparation of Ketoprofen with Trimethylated a-, b- and g-Cyclodextrins in Capillary Electrophoresis and Study of Related Selector-Selectand Interactions using Nuclear Magnetic Resonance Spectroscopy. S. Samakashvili, A. Salgado, G. K. E. Scriba, B. Chankvetadze, Chirality 2013, 25, 79-88.
Recent Advances in Electrodriven Enantioseparations. P. Jáč, G. K. E. Scriba, J. Sep. Sci. 2013, 36, 52-74.
Capillary electrophoretic study of the degradation pathways and kinetics of the aspartyl model tetrapeptide Gly-Phe-Asp-GlyOH in alkaline solution. C. Brückner, D. Imhof, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2013, 76, 96-103.
Isomerization and Epimerization of the Aspartyl Tetrapeptide Ala-Phe-Asp-GlyOH at pH 10 – a Capillary Electrophoresis Study. C. Brückner, S.-C. Bunz, D. Imhof, C. Neusüß, G. K. E. Scriba, Electrophoresis 2013, 34, 2666-2673.
Stereospecific micellar electrokinetic chromatography assay of methionine sulfoxide reductase enzymes employing a multiple layer coated capillary. Q. Zhu, R. G. El-Mergawy, S. H. Heinemann, R. Schönherr, P. Jáč, G. K. E. Scriba, Electrophoresis 2013, 34, 2712-2717.
Separation of 5-Lipoxygenase Metabolites using Cyclodextrin-Modified Microemulsion Electrokinetic Chromatography and Head Column Field Amplified Sample Stacking. H. Abromeit, O. Werz, G. K. E. Scriba, Chromatographia 2013, 76, 1187-1192.
Solid Phase Extraction of 5-Lipoxygenase Metabolites and Effect on Head-Column Field-Amplified Sample Stacking in Micellar Electrokinetic Chromatography. H. Abromeit, F. Wu, G. K.E. Scriba, J. Sep. Sci. 2013, 36, 3592-3598.
2012
The Absolute Configuration of (+)-Mefloquine, the Side Effect Reducing Enantiomer of the Antimalaria Drug Lariam. M. Schmidt, H. Sun, P. Rogne, G. K. E. Scriba, C. Griesinger, L. T. Kuhn, U. M. Reinscheid, J. Am. Chem. Soc. 2012, 134, 3080-3083.
Human skin permeation of neutral species and ionic species: Extended linear free-energy relationship analyses. K. Zhang, G. K. E. Scriba, M. H. Abraham, A. Fahr, X. Liu, J. Pharm. Sci. 2012, 101, 2034-2044.
Separation of enantiomers of norephedrine by capillary electrophoresis using cyclodextrins as chiral selectors: Comparative CE and NMR studies. K. Lomsadze, E. Domínguez Vega, A. Salgado, A. L. Crego, G. K.E. Scriba, M. L. Marina, B. Chankvetadze, Electrophoresis 2012,33, 1637-1647.
A new non-peptide substrate of human sirtuin in a capillary electrophoresis based assay. Investigation of the binding mode by docking experiments. H. Abromeit, S. Kannan, W. Sippl, G. K.E. Scriba, Electrophoresis 2012, 33, 1652-1659.
Chiral Recognition Mechanisms in Analytical Separation Sciences. G. K. E. Scriba, Chromatographia 2012, 75, 815-838.
Degradation Kinetics of an Aspartyl Tripeptide-Derived Diketopiperazine Under Forced Conditions. C. Brückner, D. Imhof, A. Fahr, G. K. E. Scriba, J. Pharm. Sci. 2012, 101, 4178-4190.
CE-MS Identification of Amino Acid Sequence Inversion as a New Degradation Pathway of an Aspartyl Model Tripeptide. C. Brückner, S.-C. Bunz, C. Neusüß, G. K. E. Scriba, Chromatographia 2012, 75, 1205-1210.
Chemometrics-Guided Development of a Cyclodextrin-Modified Micellar Electrokinetic Chromatography Method with Head Column Field Enhanced Sample Stacking for the Analysis of 5-Lipoxygenase Metabolites. H. Abromeit, A. Schaible, O. Werz, G. K. E. Scriba, J. Chromatogr. A 2012, 1267, 217-223.
Evidence of Stereoselective and Segmantal-Dependent Transport of Chiral Antidiabetic Drug Nateblinide along the Rat Small Intestine: Possible Role of Efflux Transporters. S. Maddi, S. K. Yamsami, A. Devandela, G. K. E. Scriba, M. R. Yamsani, Med. Chem. Res. 2012, 22, 2403-2410.
2011
A weak cation-exchange monolith as stationary phase for the separation of peptide diastereomers by capillary electrochromatography. R. Ludewig, S. Nietzsche, G. K. E. Scriba, J. Sep. Sci., 2011, 34, 64-69.
Capillary electrophoresis-based sirtuin assay using non-peptide substrates. Y. Fan, M. Hense, R. Ludewig, C. Weisgerber, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2011, 54, 772-778.
Fundamental aspects of chiral electromigration techniques and application in pharmaceutical and biomedical analysis. G. K. E. Scriba, J. Pharm. Biomed. Anal. 2011, 55, 688-701.
Linear Free Energy Relationship (LFER) Analysis of Retention Factors in Cerasome Electrokinetic Chromatography (EKC) Intended for Predicting Drug Skin Permeation. K. Zhang, M. Chen, G. K. E. Scriba, M. H. Abraham, X. Liu, A. Fahr, J. Pharm. Sci. 2011, 100, 3105-3113.
Identification and Characterization of Impurities of Tetracosactide by Capillary Electrophoresis and Liquid Chromatography coupled to Time-of-Flight Mass Spectrometry. A. Taichrib, G. K. E. Scriba, C. Neusüß, Anal. Bioanal. Chem. 2011, 401, 1365-1375.
Stereoselective Binding of Chrial Antidiabetic Drug Nateglinide to Plasma Proteins. S. Maddi, G. K. E. Scriba, Y. Madhusudan Rao, Drug Metabol. Drug Interact. 2011, 26, 81-86.
Separation of enantiomers of ephedrine by capillary electrophoresis using cyclodextrins as chiral selectors: Comparative CE, NMR and high resolution MS studies. E. D. Vega, K. Lomsadze, L. Chankvetadze, A. Salgado, G. K. E. Scriba, E. Calvo, J. A. López, A. L. Crego, M. L. Marina, B.Chankvetadze, Electrophoresis 2011, 32, 2640-2647.
Development and validation of a capillary electrophoresis assay for the determination of the stereoisomeric purity of chloroquine enantiomers. S. Wongwan, G. K. E. Scriba, Electrophoresis 2011, 32, 2669-2672.
Chiral electromigration techniques in pharmaceutical and biomedical analysis. G. K. E. Scriba, Bioanal. Rev. 2011, 3, 95-114.
2010 und früher
Capillary Electrophoresis Analysis of the Degradation of the Aspartyl Tripeptide Phe-Asp-GlyOH at pH 2.0 and 7.4 Under Forced Conditions. U. Conrad, A. Taichrib, C. Neusüß, G. K.E. Scriba, J. Pharm. Biomed. Anal. 2010, 51, 640-648.
Application of Phase Optimized Liquid Chromatography to Peptide Separations. J. Lu, M. Ji, R. Ludewig, G. K. E. Scriba, D. Chen, J. Pharm. Biomed. Anal. 2010, 51, 764-767.
Stereoselective Plasma Protein Binding of Amoldipine. S. Maddi, Y. Madhusudan Rao, A. Seeling, G. K. E. Scriba, Chirality 2010, 22, 262-266.
Drug-Membrane Interaction on Immobilized Liposome Chromatography Compared to Immobilized Artificial Membrane (IAM) Chromatography, Liposome/Water and n-Octanol/Water Systems. X. Liu, P. Fan, M. Chen, G. K. E. Scriba, D. Gabel, A. Fahr, Helv. Chim. Acta 2010, 93, 203-211.
Separation of Peptide Diastereomers by Capillary Electrochromatography on a Hydrophobic Monolith. R. Ludewig, J. Dong, H. Zou, G. K.E. Scriba, J. Sep. Sci. 2010, 33, 1085-1089.
Capillary Electrophoresis Assay for Simultaneous Determination of Charged and Neutral Impurities in Dexamphetamine Sulfate Using a Dual Cyclodextrin System. S. Wongwan, B. Sungthong, G. K.E. Scriba, Electrophoresis 2010, 31, 1475-1481.
Characterization of Negatively Charged a-, b-, and g-Cyclodextrin Derivatives and their Application to the Separation of Dipeptide and Tripeptide Enantiomers by Capillary Electrophoresis. B. Sungthong, R. Ivanyi, S.-C. Bunz, C. Neusüß, G. K. E. Scriba, Electrophoresis 2010, 31, 1498-1505.
Kinetics of Aspartic Acid Isomerization and Enantiomerization in Model Aspartyl Tripeptides under Forced Conditions. U. Conrad, A. Fahr, G. K. E. Scriba, J. Pharm. Sci. 2010, 99, 4162-4173.
Investigation of the pH-dependent complex formation between b-cyclodextrin and dipeptide enantiomers by capillary electrophoresis and calorimetry. I. V. Terekhova, M. Hammitzsch-Wiedemann, Y. Shi, B. Sungthong, G. K. E. Scriba, J. Sep. Sci. 2010, 33, 2499-2505.
Advances in capillary electrophoretic enzyme assays. Y. Fan, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2010, 53, 1076-1090.
Impurity profiling of dexamphetamine sulfate by cyclodextrin-modified microemulsion electrokinetic chromatography. S. Wongwan, G. K. E. Scriba, Electrophoresis 2010, 31, 3006-3011.
An integrated on-chip sirtuin assay. S. Ohla, R. Beyreiss, G. K. E. Scriba, Y. Fan, D. Belder, Electrophoresis 2010, 31, 3263-3267.
Electrophoretically-mediated microanalysis assay for sirtuin enzymes. Y. Fan, G. K. E. Scriba, Electrophoresis, 2010, 31, 3874-3880.
Electrophoretically-mediated microanalysis assay for sirtuin enzymes. Y. Fan, G. K. E. Scriba, Electrophoresis, 2010, 31, 3874-3880.
Fmoc-Peptides as Substrates in a Capillary Electrophoresis-Based Assay for Sirtuin Enzymes. Y. Fan, R. Ludewig, G. K. E. Scriba, Anal. Biochem. 2009, 387, 243-248.
Stability of Piritramide for Patient-Controlled Analgesia (PCA). D. Remane, G. K. E. Scriba, W. Meißner, M. Hartmann, Pharmazie, 2009, 64, 380-381.
Recent Developments in Peptide Stereoisomer Separations by Capillary Electromigration Techniques. G. K. E. Scriba, Electrophoresis 2009, 30, S222-S228.
Using Cyclodextrins to Achieve Chiral and Non-chiral Separations in Capillary Electrophoresis. G. K. E. Scriba, K. D. Altria, LCGC Europe, 2009, 22, 420-430.
Stability of Alemtuzumab in Infusion Bags. M. Kupfer, G. K. E. Scriba, M. Harmtann, Pharmazie, 2009, 64, 622-623.
Profiling of Levoamphetamine and Related Substances in Dexamphetamine Sulfate by Capillary Electrophoresis. N. G. Kokiashvili, S. Wongwan, C. Landgraf, K. Michaelis, M. Hammitzsch-Wiedemann, G. K.E. Scriba, J. Pharm. Biomed.Anal. 2009, 50, 1050-1053.
Effect of Urea on Analyte Complexation by 2,6-Dimethyl-b-Cyclodextrin in Peptide Enantioseparations. M. Hammitzsch-Wiedemann, G. K. E. Scriba, Electrophoresis, 2009, 30, 3764-3771.
Mathematical Approach by a Selectivity Model for Rationalization of pH- and Selector Concentration-Dependent Reversal of the Enantiomer Migration Order in Capillary Electrophoresis. M. Hammitzsch-Wiedemann, G. K. E. Scriba, Anal. Chem. 2009, 81, 8765-8773.
Effect of Fluconazole on the Pharmacokinetics of Halofantrine in Healthy Volunteers. C. P. Babalola, Y. Kolade, A. A. Olaniyi, A. Adedapo, G. K. E. Scriba, J. Clin. Pharm. Ther. 2009, 34, 677-682.
Determination of Related Substances of Levodopa Including the (R)-Enantiomer by Capillary Electrophoresis. S. Wongwan, M. Hammitzsch-Wiedemann, G. K.E. Scriba, Electrophoresis, 2009, 30, 3891-3896.
Effect of kolanut (a caffeine-containing nut) on the solubility and pharmacokinetics of halofantrine. Y. T. Kolade, C. P. Babalola, A. A. Olaniyi, G. K. E. Scriba, Eur. J. Clin. Pharmacol., 2008, 64, 77-81.
Development and Validation of a Capillary Electrophoresis Method for the Simultaneous Determination of Impurities of Escitalopram Including the R-Enantiomer. B. Sungthong, P. Jac, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2008, 46, 959-965.
Cyclodextrins in Capillary Electrophoresis Enantioseparations – Recent Developments and Applications. G. K. E. Scriba, J. Sep. Sci. 2008, 31, 1991-2011.
Retention behavior of neutral, positively and negatively charged solutes on immobilized artificial membrane (IAM) stationary phase. X. Liu, H. Hefesha, G. K. E. Scriba, A. Fahr, Helv. Chim. Acta 2008, 91, 1505-1512.
Lipophilicity Measurement of Drugs by Reversed Phase HPLC over Wide pH Range Using an Alkaline-Resistant Silica-Based Stationary Phase, XBridgeTM Shield RP18. X. Liu, H. Hefesha, H. Tanaka, G. K. E. Scriba, A. Fahr, Chem. Pharm. Bull. 2008, 56, 1417-1422.
Development of a Capillary Electrophoresis-Based Assay of Sirtuin Enzymes. Y. Fan, R. Ludewig, D. Imhof, G. K. E. Scriba, Electrophoresis, 2008, 29, 3717-3723.
Capillary Electrophoresis Analysis of Hydrolysis, Isomerization and Enantiomerization of Aspartyl Model Tripeptides in Acidic and Alkaline Solution. S. De Boni, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2007, 43, 49-56.
Comparison of cyclodextrin-dipeptide inclusion complexes in the absence and presence of urea by means of capillary electrophoresis, nuclear magnetic resonance and molecular modeling. B. Wabel, J. Scheiber, C. Meier, M. Hammitzsch, K. Baumann, G. K. E. Scriba, U. Holzgrabe, Eur. J. Org. Chem. 2007, 2921-2930.
Non-Aqueous Capillary Electrophoresis-Mass Spectrometry. G. K. E. Scriba, J. Chromatogr. A 2007, 1159, 28-41. Development and validation of a stereoselective HPLC method for the determination of the in vitro transport of nateglinide enantiomers in rat intestine. M. Srinivas, K. Srisailam, E. Chandra Mohan, Y. Madhusudan Rao, G. K. E. Scriba, J. Sep. Sci. 2007, 30, 1875-1880.
Influence of Buffer Substances and Urea on the b-Cyclodextrin-Mediated Chiral Separation of Dipeptides in Capillary Electrophoresis. M. Hammitzsch, G. K. E. Scriba, Electrophoresis 2007, 28, 2619-2628.
Comprehensive profiling of the complex dendrimeric contrast agent Gadomer using a combined approach of capillary electrophoresis, mass spectrometry and capillary electrophoresis - mass spectrometry. K. Vetterlein, U. Bergmann, K. Büche, M. Walker, J. Lehmann, M. W. Linscheid, G. K. E. Scriba, M. Hildebrand, Electrophoresis, 2007, 28, 3088-3099.
Study on complex formation of biologically active pyridine derivatives with cyclodextrins by capillary electrophoresis. I. V. Terekhova,G. K. E. Scriba, J. Pharm. Biomed. Anal. 2007, 45, 688-693.
Substituted 2-Thioxo-imidazolidin-4-ones and Imidazolidin-2,4-diones: New Fatty Acid Amide Hydrolase Inhibitor Templates.. G. G. Muccioli, N. Fazio, G. K. E. Scriba, W. Poppitz, F. Cannata, J. H. Poupaert, J. Wouters, D. M. Lambert, J. Med. Chem. 2006, 49, 417-425.
Recent Advances in Peptide and Peptidomimetic Stereoisomer Separations by Capillary Electromigration Techniques. G. K. E. Scriba, Electrophoresis 2006, 27, 222-230.
Synthesis and Activity of 1,3,5-triphenyl-imidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxo-imidazolidin-4-ones : Characterization of new CB1 Cannabinoid Receptor Inverse Agonists/Antagonists.. G. G. Muccioli, J. Wouters, G. K. E. Scriba, T. Pizza, P. Di Pace, P. De Martino, J. H. Poupaert, D. M. Lambert, J. Med.Chem. 2006, 49, 872-882.
Detection of New Amino Acid Sequences of Alamethicin F30 by Nonaqueous Capillary Electrophoresis - Mass Spectrometry. A. Psurek, C. Neusüß, M. Pelzing, T. Degenkolb, H. Brückner, G. K. E. Scriba, J. Pep. Sci. 2006, 12, 279-290.
Determination of Enkephalin Peptides by Nonaqueous Capillary Electrophoresis with Electrochemical Detection. A. Psurek, F.-M. Matysik, G. K. E. Scriba, Electrophoresis 2006, 27, 1199-1208.
Analysis of the antimalarial drug halofantrine and its major metabolite N-desbutylhalofantrine in human plasma by high performance liquid chromatography. Y. T. Kolade, C. P. Babalola, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2006, 41, 315-319.
Analysis of Lipophilic Peptides by Nonaqueous Capillary Electrophoresis. A. Psurek, S. Feuerstein, D. Willbold, G. K. E. Scriba, Electrophoresis 2006, 27, 1768-1775.
Characterization of the Complex Dendrimeric Contrast Agent Gadomer by Capillary Electrophoresis. K. Vetterlein, K. Büche, M. Hildebrand, G. K. E. Scriba, J. Lehmann, Electrophoresis 2006, 27, 2400-2412.
Development and validation of a robust capillary electrophoresis method for impurity profiling of etomidate including the determination of chiral purity using a dual cyclodextrin system. M. Hammitzsch, R. Nageswara Rao, G. K. E. Scriba, Electrophoresis, 2006, 27, 4334-4344.
Synthesis and pharmacological evaluation of 2-hydroxymethylbenzamides as anti-inflammatory and analgesic agents. L. O. Okunrobo, C. O. Usifoh und G. K. E. Scriba, Acta Pol. Pharm. 2006, 63, 25-31.
Substituted 5,5’-Diphenyl-2-thioxo-imidazolidin-4-ones as CB1 Cannabinoid Receptor Ligands: Synthesis and Pharmacological Evaluation.. G. G. Muccioli, D. Martin,J. Wouters, G. K. E. Scriba, J. H. Poupaert, D. M. Lambert, J. Med. Chem. 2005, 48, 2509-2517.
1-Benzhydryl-3-phenyl-urea and 1-Benzhydryl-3-phenyl-thiourea Derivatives: New Templates among the CB1 Cannabinoid Receptor Inverse Agonists.. G. G. Muccioli, J. Wouters, G. K. E. Scriba, W. Poppitz, J. H. Poupaert, D. M. Lambert, J. Med. Chem. 2005, 48, 7486-7490.
High Performance Liquid Chromatographic Separation of Dipeptide and Tripeptide Stereoisomers Using a Chiral Crown Ether Stationary Phase. U. Conrad, B. Chankvetadze, G. K. E. Scriba, J. Sep. Sci. 2005, 28, 2275-2281.
Analysis of the Lipophilic Peptaibol Alamethicin by Nonaqueous Capillary Electrophoresis - Electrospray Ionization - Mass Spectrometry. A. Psurek, C. Neusüß, A. De La Rosa, G. K. E. Scriba, Electrophoresis 2005, 26, 4368-4378.
Analysis of Aspartyl Peptide Degradation Products by High Performance Liquid Chromatography and High Performance Liquid Chromatography-Mass Spectrometry.. S. De Boni, C. Oberthür, M. Hamburger, G. K. E. Scriba, J. Chromatogr. A 2004, 1022, 95-102.
Development and Validation of a Robust Capillary Electrophoresis Method for Impurity Profiling of Calcium Levofolinate Including the (6R,2'S)-Diastereomer Using Statistical Experimental Design.. F. Süß, V. Harang, C. E. Sänger-van de Griend, G. K. E. Scriba, Electrophoresis 2004, 25, 766-777.
Enantiomer Separations in Capillary Electrophoresis in the Case of Equal Binding Constants of the Enantiomers with a Chiral Selector: Commentary on the Feasibility of the Concept.. B. Chankvetadze, W. Lindner, G. K.E. Scriba, Anal. Chem. 2004, 76, 4256-4260.
Development and Validation of a High-Performance Liquid Chromatography Assay and a Capillary Electrophoresis Assay for the Analysis of Adenosine and the Degradation Product Adenine in Infusions. P. Kießling, G. K. E. Scriba, F. Süß, G. Werner, H. Knoth, M. Hartmann, J. Pharm. Biomed. Anal. 2004, 36, 535-339.
A Rapid and Efficent Microwave-Assisted Synthesis of Hydantoins and Thiohydantoins.. G. Muccioli, J. H. Poupaert, J. Wouters, B. Norberg, W. Poppitz, G. K. E. Scriba, D. M. Lambert, Tetrahedron 2003, 59, 1301-1307.
Peptide Separations and Dissociation Constants in Nonaqueous Capillary Electrophoresis – Comparison of Methanol and Aqueous Buffers.. A. Psurek, G. K. E. Scriba, Electrophoresis 2003, 24, 765-773.
Identification of Degradation Products of Aspartyl Tripeptides by Capillary Electrophoresis-Tandem Mass Spectrometry.. S. De Boni, C. Neusüß, M. Pelzing, G. K. E. Scriba, Electrophoresis 2003, 24, 874-882.
Migration Order of Dipeptide and Tripeptide Enantiomers in the Presence of Single Isomer and Randomly Sulfated Cyclodextrins as a Function of pH.. F. Süß, C. E. Sänger-van de Griend, G. K. E. Scriba, Electrophoresis 2003, 24, 1069-1076.
Effects of Systemically Administered Taurine and N-Pivaloyltaurine on Striatal Extracellular Dopamine and Taurine in Freely Moving Rats.. J. Salimäki, G. K. E. Scriba, T. P. Piepponen, N. Rautolahti, L. Ahtee, Naunyn Schmiedbergs Arch. Pharmacol. 2003, 368, 134-141.
Pharmaceutical and Biomedical Applications of Chiral Capillary Electrophoresis and Capillary Electrochromatography: An Update.. G. K. E. Scriba, Electrophoresis 2003, 24, 2409-2421.
Oral Testosterone-Triglyceride Conjugate in Rabbits: Single-dose Pharmacokinetics and Comparison with Oral Testosterone Undecanoate. J. K. Amory, G. K. E. Scriba, D. W. Amory, W. J. Bremner, J. Andrology, 2003, 24, 716-720.
High Performance Liquid Chromatographic Determination of Pyronaridine in Human Plasma and Oral Dosage Form.. C. P. Babalola, G. K. E. Scriba, A. Sowunmi, O. A. Alawode, J. Chromatogr. B 2003, 795, 265-272.
Versatile Access to Benzhydryl-Phenylureas through an Unexpected Rearrangement during Microwave-Enhanced Synthesis of Hydantoins.. G. G. Muccioli, J. Wouters, J. H. Poupaert, B. Norberg, W. Poppitz, G. K. E. Scriba, D. M. Lambert, Org. Lett. 2003, 5, 3599-3602.
Recent Advances in Enantioseparation of Peptides by Capillary Electrophoresis.. G. K. E. Scriba, Electrophoresis 2003, 24, 4063-4077.
Selected Fundamental Aspects of Chiral Electromigration Techniques and their Application to Pharmaceutical and Biomedical Analysis. G. K. E. Scriba, J. Pharm. Biomed. Anal. 2002, 27, 373-399.
Enantioseparation of New Chiral Hydantoin Derivatives Using HPLC on Polysaccharide Type Chiral Stationary Phases. I. Kartozia, M. R. Kanyonyo, D. M. Lambert, G. K. E. Scriba, B. Chankvetadze, J. Pharm. Biomed. Anal. 2002, 27, 457-465.
Studies on the Chiral Recognition of Peptide Enantiomers by Neutral and Sulfated β-Cyclodextrin and Heptakis-(2,3-di-O-acetyl)-β-cyclodextrin Using Capillary Electrophoresis and Nuclear Magnetic Resonance. F. Süß, C. Kahle, U. Holzgrabe, G. K. E. Scriba, Electrophoresis 2002, 23, 1301-1307.
Separation of Dipeptide and Tripeptide Enantiomers in Capillary Electrophoresis by the Cationic Cyclodextrin Derivative 2-Hydroxypropyltrimethylammonium-β-cyclodextrin and by neutral β-Cyclodextrin Derivatives at alkaline pH.. S. Süß, W. Poppitz, G. K. E. Scriba, J. Sep. Sci., 2002, 25, 1147-1154
Development and Validation of a Capillary Electrophoresis Assay for the Determination of 3,4-Diaminopyridine and 4-Aminopyridine Including Related Substances. S. Sabbah, G. K. E. Scriba, J. Chromatogr. A 2001, 907, 321-328.
Validation of a Capillary Electrophoresis Assay for the Analysis of Isomeric Aminopyridines and Diaminopyridines. S. Sabbah, G. K. E. Scriba, J. Pharm. Biomed. Anal. 2001, 24, 695-703.
Separation of Dipeptide and Tripeptide Enantiomers in Capillary Electrophoresis Using Carboxymethyl-β-Cyclodextrin and Succinyl-β-Cyclodextrin. Influence of the Amino Acid Sequence, Nature of the Cyclodextrin and pH. S. Sabbah, G. K. E. Scriba, Electrophoresis 2001, 22, 1385-1393.
Analysis of Aminopyridines and Diaminoypridines by Capillary Electrophoresis. S. Sabbah, M. Abu-Khurmah, H. Oelschläger, G. K. E. Scriba, Chromatographia 2001, 53, 559-562.
Synthesis and Anticonvulsant Activity of N,N-Phthaloyl Derivatives of Central Nervous System Inhibitory Amino Acids. C. O. Usifoh, D. M. Lambert, H. Wouters, G. K. E. Scriba, Arch. Pharm. Pharm. Med. Chem., 2001, 334, 323-331.
Method Development and Validation for the Chiral Separation of Peptides in the Presence of Cyclodextrins Using Capillary Electrophoresis and Experimental Design.. Y. Loukas, S. Sabbah, G. K. E. Scriba, J. Chromatogr. A, 2001, 931, 141-152.
Influence of the Amino Acid Sequence and Nature of the Cyclodextrin on the Separation of Small Peptide Enantiomers Using Randomly Substituted and Single Isomer Sulfated Cyclodextrins in Capillary Electrophoresis. F. Süß, W. Poppitz, C. E. Sänger-van de Griend, G. K. E. Scriba, Electrophoresis 2001, 22, 2416-2423.
pH-Dependence of Complexation Constants and Complex Mobility in Capillary Electrophoresis Separations of Dipeptide Enantiomers. S. Sabbah, F. Süß, G. K. E. Scriba, Electrophoresis 2001, 22, 3163-3170.
Comparison of α-, β-, γ-Cyclodextrins and their Hydroxypropyl Derivatives for the Separation of Peptide Enantiomers in Capillary Electrophoresis. N. Sidamonidze, F. Süß, W. Poppitz, G. K. E. Scriba, J. Sep. Sci. 2001, 24, 777-783.
Bisphosphonates - A Survey (in German). G. K. E. Scriba, PharmuZ. 2000, 29, 50-56. Effect of Flavonol Derivatives on the Carrageenin-Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase and 5-Lipoxygenase in Vitro. A. M. Sobottka, W. Werner, G. Blaschke, G. Dannhardt, E. E. S. Schapoval, E. P. Schenkel, G. K. E. Scriba, Arch. Pharm. Pharm.Med. Chem. 2000, 333, 205-210.
Influence of the Structure of Cyclodextrins and Amino Acid Sequence of Dipeptides and Tripeptides on the pH-Dependent Reversal of the Migration Order in Capillary Electrophoresis. S. Sabbah, G. K. E. Scriba, J. Chromatogr. A 2000, 894, 267-272.
Synthesis and Anticonvulsant Activity of Acetylenic Quinazolinone Derivatives. C. O. Usifoh, G. K. E. Scriba, Arch. Pharm. Pharm. Med. Chem. 2000, 333, 261‑266.
Analysis of Isomeric Glutamyl Peptides by Capillary Electrophoresis. Application to Stability Studies. S. C. Schücker, G. K. E. Scriba, J. Chromatogr. A 2000, 888, 275-279.
Drug-Phospholipid Conjugates as Potential Prodrugs: Synthesis, Characterization, and Degradation by Pancreatic Phospholipase A2. M. Kurz, G. K. E. Scriba, Chem. Phys. Lipids 2000, 107, 143-157.
Analysis of Di- and Tripeptides in Capillary Electrophoresis: Comparison between 18‑Crown-6-Tetracarboxylic Acid and Carboxymethyl-β-
Cyclodextrin. K. Verleysen, S. Sabah, G. K. E. Scriba, P. Sandra, Chromatographia 1999, 49, 215‑218.
pH-Dependent Reversal of the Chiral Recognition of an Aspartyl Tripeptide by Carboxymethyl-β-Cyclodextrin. S. Sabah, G. K. E. Scriba, J. Chromatogr. A 1999, 833, 261-266.
Pancreatic Lipase Mediated Drug Delivery using Drug-Glyceride Prodrugs (in German). G. K. E. Scriba, Pharm. u. Z. 1999, 28, 87-94.
Synthesis and Anticonvulsant Activity of N-Benzyloxycarbonyl-Amino Acid Prodrugs of Phenytoin. G. K. E. Scriba, D. M. Lambert, J. Pharm. Pharmacol. 1999, 51, 549-553.
N-Benzyloxycarbonylglycine Esters and Amides as new Anticonvulsants. M. Guerts, J. H. Poupaert, G. K. E. Scriba, D. M. Lambert, J. Med. Chem., 1998, 41, 24-30.
Determination of Aspartame and its Degradation and Epimerization Products by Capillary Electrophoresis. S. Sabah, G. K. E. Scriba, J. Pharm. Biomed. Anal. 1998, 16, 1089-1096.
Resolution of Aspartic Acid-Containing Dipeptide and Tripeptide Stereoisomers by Capillary Electrophoresis. S. Sabah, G. K. E. Scriba, J. Microcol. Sep. 1998, 10, 255-258.
Electrophoretic Stereoisomer Separation of Aspartyl Dipeptides and Tripeptides in Untreated Fused-Silica and Polyacrylamide-Coated Capillaries Using Charged Cyclodextrins. S. Sabah, G. K. E. Scriba, J. Chromatogr. A 1998, 822, 137-145.
Evaluation of the Enantioselective Possibilities of Highly Sulfated Cyclodextrins for the Separation of Di- and Tripeptides. K. Verleysen, S. Sabah, G. K. E. Scriba, A. Chen, P. Sandra, J. Chromatogr. A 1998, 824, 91-97.
Bioavailability of Phenytoin and Anticonvulsant Activity after Oral Administration of Phenytoin-bis-hydroxyisobutyrate to Rats. G. K. E. Scriba, D. M. Lambert, Pharm. Res. 1997, 14, 251-253.
Anticonvulsant Activity of Ester- and Amide-Type Lipid Conjugates of Glycine and N‑Benzyloxycarbonylglycine. D. M. Lambert, G. K. E. Scriba, J. H. Poupaert, P. Dumont, Eur. J. Pharm. Sci. 1996, 4, 159-166.
Bioavailability and Anticonvulsant Activity of 2-Cyanoguanidinephenytoin, a Structural Analogue of Phenytoin. D. M. Lambert, B. Masereel, B. Gallez, M. Guerts, G. K. E. Scriba, J. Pharm. Sci. 1996, 85, 1077-1081.
3-Hydroxymethylphenytoin Valproic Acid Ester, A New Prodrug Combining Two Anticonvulsant Drugs. G. K. E. Scriba, Arch. Pharm. Pharm. Med. Chem. 1996, 329, 554-555.
Glyceride Conjugates as Drug Carriers. D. M. Lambert, G. K. E. Scriba, B. Gallez, J. H. Poupaert, Curr. Med. Chem. 1995, 2, 376-391.
Synthesis and in Vitro Degradation of Testosterone-Lipid Conjugates. G. K. E. Scriba, Arch. Pharm. 1995, 328, 271-276.
Anticonvulsant Activity of Phenytoin-Lipid Conjugates, A New Class of Phenytoin Prodrugs. G. K. E. Scriba, D. M. Lambert, J. H. Poupaert, J. Pharm. Pharmacol. 1995, 47, 197‑203.
Bioavailability and Anticonvulsant Activity of a Monoglyceride-Derived Prodrug of Phenytoin after Oral Administration to Rats. G. K. E. Scriba, D. M. Lambert, J. H. Poupaert, J. Pharm. Sci. 1995, 84, 300 - 302.
Derivés simples d`acides aminés neurotransmetteurs. Evaluation anticonvulsante de derivés amides, carbamates et esters de la glycine et de la β-alanine.. D. M. Lambert, M. Geurts, G. K. E. Scriba, J. H. Poupaert, P. Dumont, J. Pharm. Belg. 1995, 50, 194-203.
Pankreaslipase-vermitteltes Drug Delivery zur Verbesserung der oralen Bioverfügbarkeit schwerlöslicher Arzneistoffe (in German). G. Scriba, habilitation thesis, University of Münster, 1995.
2-Cyanimino-5,5-diphenylimidazolinone Monohydrate. L. Dupont, B. Masereel, D. M. Lambert, G. K. E. Scriba, Acta Cryst. 1995, C51, 1901-1903.
Bioavailability of Phenytoin Following Oral Administration of Phenytoin-Lipid Conjugates to Rats. G. K. E. Scriba, D. M. Lambert, J. H. Poupaert, J. Pharm. Pharmacol. 1995, 47, 945‑948.
Synthesis and in Vitro Evaluation of 4-(2-Glyceryl)butyric Acid: A Glyceride Mimic for Drug Delivery via Drug-Lipid Conjugates. G. K. E. Scriba, Arch. Pharm. 1994, 327, 347-348.
Phenytoin-Lipid Conjugates as Potential Prodrugs of Phenytoin. G. K. E. Scriba, Arch. Pharm. 1993, 326, 477-481.
Phenytoin-Lipid Conjugates: Chemical, Plasma Esterase- and Pancreatic Lipase-Mediated Hydrolysis in Vitro. G. K. E. Scriba, Pharm. Res. 1993, 10, 1181-1186.
Metabolism of Catecholamine Prodrugs in Cultured Bovine Brain Microvessel Endothelial Cells. G. K. E. Scriba, R. T. Borchardt, NATO ASI Ser., Ser. A, 1991, 191-202.
Metabolism of Catecholamine Esters by Bovine Brain Microvessel Endothelial Cells. G. K. E. Scriba, R. T. Borchardt, J. Neurochem. 1989, 153, 610-615.
Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by Bovine Brain Microvessel Endothelial Cells. G. K. E. Scriba, R. T. Borchardt, Brain Res. 1989, 501, 175-178.
Effect of Ibopamine and the Active Metabolite Epinine on the Catecholamine Content of Rat Hypothalamus and Brainstem in Vitro. G. K. E. Scriba, J. A. Hower, N. Y. Liang, P. V. Fennessey, R. T. Borchardt, J. Pharmacol. Exp. Ther. 1988, 247, 609-616.
Selected-Ion Monitoring Gas Chromatographic-Mass Spectrometric Analysis of Catecholamines: Enhancement of Sensitivity by a
Simple Clean-up Step on Sephadex G-10. G. K. E. Scriba, R. T. Borchardt, J. A. Zirrolli, P. V. Fennessey, J. Chromatogr. 1988, 433, 31-40.
The Biosynthesis of Cularine. G. Blaschke and G. Scriba, Phytochemistry 1986, 25, 111-113.
New Fumariaceae Alkaloids Including the Biogenetic Precursor of Cularine. G. Blaschke, G. Scriba, Phytochemistry 1985, 24, 585-588.
Neue Alkaloide aus Corydalis claviculata DC. Biogenese des Cularins (in German). G. Scriba, Ph.D. thesis, University of Münster, 1984.
New Papaveraceae Alkaloids Including an 7,8-Oxygenated Isoquinoline, the Postulated Precursor of the Cularine Alkaloids. G. Blaschke, G. Scriba; Z. Naturforsch. 1983, 38C, 670-671.
The Biosynthesis of Cularine. G. Blaschke, G. Scriba, Tetrahedron Lett. 1983, 24, 5855-5856.