Jena

Sections of the Institute

Pharmaceutical/Medicinal Chemistry

Prof. Dr. Oliver Werz investigates mechanisms of action and targets of anti-inflammatory and anti-neoplastic compounds at the molecular and cellular level. In addition, Prof. Werz is searching for new therapeutic drugs for the treatment of inflammations, autoimmune diseases, neurodegenerative diseases and tumors. An important aspect of the research is gender-specific differences in pharmacotherapy (“gender medicine”).

Prof. Dr. Gerhard Scriba develops highly specialized, modern analytical separation techniques, particularly for purity testing of pharmaceutical drugs. The research includes the development of new methods for the separation of stereoisomers, mechanistic examination of the interaction between analyte and selector and the development of capillary electrophoresis-based enzyme assays.

Websites Pharmaceutical/Medicinal Chemistry

Secretariat
Theresa Hildebrandt
Philosophenweg 14
07743 Jena
Phone
+49 4641 9-49800
Fax
+49 4641 9-49802
Opening hours:

Montag 8-11 Uhr
Dienstag 8-11 Uhr
Mittwoch geschlossen
Donnerstag 8-11 Uhr
Freitag 8-10 Uhr

Pharmaceutical Microbiology

Research in Prof. Dirk Hoffmeister's group focuses on basidiomycete natural products. The research aims at elucidation of biosyntheses and biotechnological production of bioactive compounds, along with the function of the compounds for their producers.

Websites Pharmaceutical Microbiology

Secretariat
Christine Steinbach
Winzerlaer Straße 2
07745 Jena
Phone
+49 3641 9-49850
Fax
+49 3641 9-49852

Pharmaceutical Biology

Prof. Dr. Thomas Winckler is interested to uncover the molecular mechanisms that certain mobile genetic elements use to identify specific integration sites in the genome of the "social amoeba" Dictyostelium discoideum. The pharmaceutical perspective of this research is to improve current retroviral gene therapy vectors with a component that may help reduce the genotoxicity of such vectors. In another research field Prof. Winckler is interested to determine how individual cells of social amoeba communicate with each other during the aggregation of single cells into multicellular organisms that later form fruiting bodies. Finally, Prof. Winckler is using cell-based and other assays to uncover new lead structures as NMDA receptor antagonists that may be useful as drugs for the therapy of Alzheimer´s disease.

Websites Pharmaceutical Biology

Secretariat
Angela Reimann
Semmelweisstraße 10
07743 Jena
Phone
+49 3641 9-49840
Fax
+49 3641 9-49842
Opening hours:

Im Sekretariat Semmelweisstraße 10 werden die Studienleistungen im Studiengang Pharmazie verwaltet.

Sprechzeiten für Studierende:
Montag bis Freitag
10-11 Uhr und 14.30-15.30 Uhr

Pharmaceutical Technology

Prof. Dr. Dagmar Fischer works on the development, formulation, characterization and biopharmaceutic testing of nanoparticular drug application systems composed of either synthetic or natural polymers. A focus of the work is on the formulation of innovative drugs including poorly soluble natural products and biomacromolecular drugs and includes the development of methods for cell- and tissue-specific targeting. In addition, Prof. Fischer is interested in the interaction of nanoparticular medicinal products with biological barriers including skin, blood-brain barrier, tumors and intestine, and the testing in models alternative to animal testing (3R model), such as the hen egg test.

Over the years Prof. Dr. Paola Luciani focused her research on the design and characterization of liposomes as drug delivery system (protein, nucleic acids, drugs). She has expertise in designing contrast agents for non-invasive fluorescence imaging of lymphatic and vascular system in inflammation and cancer, as well as selectively sensing reactive oxygen species. Prof. Luciani's research is characterized by a multidisciplinary approach aimed at developing lipid-based tools for diagnostic molecular imaging and for targeted therapy of fibrotic diseases. Another research focus is understanding the molecular mechanisms and the interecellular communication underlying the oral administration of lipid-based formulations and the effect of oxidative stress on phospholipids as nutraceuticals. More recently Prof. Luciani started to explore the field of site-specific sustained release and her research groups actively works on the development of novel manufacturing processes for lipid-based depots as an alternative to current technologies for hydrophilic drugs and biomacromolecules.

Websites Pharmaceutical Technology

Secretariat
Jessica Hiepe
Lessingstraße 8
07743 Jena
Phone
+49 3641 9-49900
Fax
+49 3641 9-49902
Opening hours:

Lessingstraße 8:
Mo-Fr von 7:30-11:30 Uhr
Telefon: +49 3641 9-49900

Otto-Schott-Straße 41:
Mo-Fr von 12:30 - 16:30 Uhr
Telefon: +49 3641 9-49940

Clinical Pharmacy

Lectures in Clinical Pharmacy are organized by PD Dr. Andreas Seeling.

Websites Clinical Pharmacy

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